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Article

SNAP predicts effect of mutations on protein function.

Bioinformatics (Oxford, England) - 15 Oct 2008

Bromberg Yana, Yachdav Guy, Rost Burkhard

Abstract excerpt

Many non-synonymous single nucleotide polymorphisms (nsSNPs) in humans are suspected to impact protein function. Here, we present a publicly available server implementation of the method SNAP (screening for non-acceptable polymorphisms) that predicts the functional effects of single amino acid substitutions. SNAP identifies over 80% of the non-neutral mutations at 77% accuracy and over 76% of the neutral...

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Identifiers

PMID: 18757876
DOI: 10.1093/bioinformatics/btn435
PMCID: PMC2562009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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