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Article

DNA hypermethylation, Her-2/neu overexpression and p53 mutations in ovarian carcinoma.

Gynecologic oncology - 1 Nov 2008

Feng Qinghua, Deftereos Georgios, Hawes Stephen E, Stern Joshua E, Willner Julia B, Swisher Elizabeth M, Xi Longfu, Drescher Charles, Urban Nicole, Kiviat Nancy

Abstract excerpt

OBJECTIVES: To define patterns of aberrant DNA methylation, p53 mutation and Her-2/neu overexpression in tissues from benign (n=29), malignant (n=100), and border line malignant ovaries (n=10), as compared to normal (n=68) ovarian tissues. Further, to explore the relationship between the presence of genetic and epigenetic abnormalities in ovarian cancers, and assess the association between epigenetic changes and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18757082
DOI: 10.1016/j.ygyno.2008.07.036
PMCID: PMC2642648

Genes

RASSF1
CABIN1
HIC1
CDH13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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