Article
Expression of EGFR and c-kit is associated with the basal-like phenotype in breast carcinomas of African women.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jun 2008
Nalwoga Hawa, Arnes Jarle B, Wabinga Henry, Akslen Lars A
Abstract excerpt
Epidermal growth factor receptor (EGFR) and c-kit are tyrosine kinase growth factor receptors which are frequently expressed in basal-like breast carcinomas, and tyrosine kinase inhibition is now a promising strategy in treatment of breast cancer. The aim of this study was to evaluate the expression of EGFR and c-kit in breast cancer with special focus on the basal-like phenotype (BLP) and other prognostic...
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