Cooperative exonization of MaLR and AluJo elements contributed an alternative promoter and novel splice variants of RNF19.

Abstract excerpt

The RNF19 protein, which contains RING-finger and IBR motifs, acts as an E3 ubiquitin ligase localized to Lewy bodies. RNF19 is located on human chromosome 8q22.2, has a 4.4-kb transcript, and is ubiquitously expressed in various tissues. Here, we identified an alternative RNF19 promoter region and alternative RNF19 transcripts derived from MaLR (mammalian apparent LTR-retrotransposon) and AluJo elements....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alternative Splicing
• Share to Alu Elements