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Article

Temperament and character as schizophrenia-related endophenotypes in non-psychotic siblings.

Schizophrenia research - 1 Sept 2008

Smith Matthew J, Cloninger C Robert, Harms Michael P, Csernansky John G

Abstract excerpt

BACKGROUND: Quantitative endophenotypes are needed to better understand the pathogenesis of schizophrenia. The psychobiological model of temperament and character suggests that personality traits are heritable and regulated by brain systems influencing schizophrenia susceptibility. Thus, measures of temperament and character may serve as schizophrenia-related endophenotypes in individuals with schizophrenia and...

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Identifiers

PMID: 18718739
DOI: 10.1016/j.schres.2008.06.025
PMCID: PMC2565802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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