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Article

Review. EGFR mutations in non-small cell lung cancer--clinical implications.

In vivo (Athens, Greece) - 1 Jan 2000

Charpidou Andriani, Blatza Despoina, Anagnostou Valsamo, Anagnostou Elsa, Syrigos Konstantinos N

Abstract excerpt

The epidermal growth factor receptor (EGFR) family members seem to play a critical role in lung tumourigenesis and are overexpressed in 40-80% of non-small cell lung carcinoma (NSCLC) tumours. EGFR activation results in a series of downstream signaling events that mediate cancer cell growth, proliferation, motility, adhesion, invasion, apoptosis inhibition and metastasis as well as resistance to chemotherapy....

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Source

Identifiers

PMID: 18712184

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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