Article
Phenotypic characterization of two Ancylostoma caninum isolates with different susceptibilities to the anthelmintic pyrantel.
Antimicrobial agents and chemotherapy - 1 Nov 2008
Kopp Steven R, Coleman Glen T, McCarthy James S, Kotze Andrew C
Abstract excerpt
The anthelmintic pyrantel plays an important role in the control of gastrointestinal helminths of humans and domestic animals. Despite the demonstration of pyrantel resistance in several helminth species over the last 20 years, the resistance mechanism remains unclear. It has been hypothesized that resistance may arise as a consequence of changes to the relative proportions of subpopulations of nicotinic...
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