Article
The detection of three independent benzimidazole resistance mutations in a single Ancylostoma caninum population from a Golden Retriever breeding kennel in Sao Paulo, Brazil.
International journal for parasitology. Drugs and drug resistance - 1 Aug 2026
Dini Mahya, Chen Rebecca, Redman Elizabeth, Leutenegger Christian M, Tereski Jeffrey, Loo Samantha, Savard Christian, Jimenez Castro Pablo D, Miyashiro Samantha Ive, Gilleard John
Abstract excerpt
Multiple anthelmintic drug resistance (MADR) is widespread in the canine hookworm Ancylostoma caninum in kenneled greyhounds in the USA and Australia with benzimidazole resistance being associated with the isotype-1 β-tubulin SNPs Q134H(CAA > CAT) and F167Y(TTC > TAC) in both cases. These two SNPs have also been found to be widespread, often at high frequency, in A. caninum populations in pet dogs across the USA...
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