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Article

TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis.

Journal of leukocyte biology - 1 Dec 2008

Ashtekar Amit R, Zhang Ping, Katz Jannet, Deivanayagam Champion C S, Rallabhandi Prasad, Vogel Stefanie N, Michalek Suzanne M

Abstract excerpt

Francisella tularensis is the causative agent of tularemia, a severe, debilitating disease of humans and other mammals. As this microorganism is also classified as a "category-A pathogen" and a potential biowarfare agent, there is a need for an effective vaccine. Several antigens of F. tularensis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18708593
DOI: 10.1189/jlb.0308215
PMCID: PMC2614597

Genes

TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18708593-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis.PMID 18708593Read ↗

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