The Arginine Catabolic Mobile Element and Staphylococcal Chromosomal CassettemecLinkage: Convergence of Virulence and Resistance in the USA300 Clone of Methicillin‐ResistantStaphylococcus aureus

Abstract excerpt

The epidemic character of community-associated methicillin-resistant Staphylococcus aureus, especially the geographically widespread clone USA300, is poorly understood. USA300 isolates carry a type IV staphylococcal chromosomal cassette mec (SCCmec) element conferring beta-lactam antibiotic class resistance and a putative pathogenicity island, arginine catabolic mobile element (ACME). Physical linkage between...

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