Article
Population structure analysis of the Mycobacterium tuberculosis Beijing family indicates an association between certain sublineages and multidrug resistance.
Antimicrobial agents and chemotherapy - 1 Oct 2008
Iwamoto Tomotada, Yoshida Shiomi, Suzuki Katsuhiro, Wada Takayuki
Abstract excerpt
Our population-based study of the Mycobacterium tuberculosis Beijing family examined the frequency of occurrence of each sublineage of this family, classified by using 10 synonymous single-nucleotide polymorphisms. The results revealed the overabundance of two evolutionary sublineages in a population of multidrug-resistant and extensively drug-resistant tuberculosis bacteria.
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