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In Vitro and In Vivo Evaluations of Oxacillin Efficiency against mecA -Positive Oxacillin-Susceptible Staphylococcus aureus

12 Aug 2008

Abstract excerpt

Community-type Staphylococcus aureus strains that are positive for mecA and PBP2a but appear phenotypically susceptible to oxacillin are increasingly reported worldwide. Four S. aureus clinical isolates carrying the mecA gene with oxacillin MICs of <2 microg/ml were tested for oxacillin efficiency by population analyses and experimental thigh infections. These isolates harbored staphylococcal cassette chromosome...

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PMID: 18694946
DOI: 10.1128/aac.00653-08

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