Article
Human models of aging and longevity.
Expert opinion on biological therapy - 1 Sept 2008
Cevenini E, Invidia L, Lescai F, Salvioli S, Tieri P, Castellani G, Franceschi C
Abstract excerpt
BACKGROUND: The aging phenotype in humans is very heterogeneous and can be described as a complex mosaic resulting from the interaction of a variety of environmental, stochastic and genetic-epigenetic variables. Therefore, each old person must be considered as a singleton, and consequently the definition of 'aging phenotype' is very difficult. OBJECTIVE: We discuss the phenotype of centenarians, the best example...
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