Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Emergence of reduced susceptibility to metronidazole in Clostridium difficile.

The Journal of antimicrobial chemotherapy - 1 Nov 2008

Baines Simon D, O'Connor Rachael, Freeman Jane, Fawley Warren N, Harmanus Celine, Mastrantonio Paola, Kuijper Ed J, Wilcox Mark H

Abstract excerpt

OBJECTIVES: Antimicrobial treatment for Clostridium difficile infection (CDI) has typically been metronidazole, although reports have questioned the efficacy of this option. We screened recently isolated C. difficile (2005-06) for susceptibility to metronidazole and compared results for historic isolates (1995-2001). METHODS: C. difficile ribotypes 001 (n = 86), 106 (n = 81) and 027 (n = 48) and isolates from the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clostridioides difficile
Share to Anti-Infective Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bacterial Typing Techniques

Share to Drug Resistance, Bacterial

Share to Enterocolitis, Pseudomembranous

Share to Metronidazole

Share to Minisatellite Repeats

Share to Ribotyping

Source

Identifiers

PMID: 18693234
DOI: 10.1093/jac/dkn313

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Emergence of reduced susceptibility to metronidazole in Clostridium difficile.PMID 18693234Read ↗

Analysis of metronidazole susceptibility in different Clostridium difficile PCR ribotypes.Semantic proximity Read ↗

Characterization of a stable, metronidazole-resistant Clostridium difficile clinical isolate.Semantic proximity Read ↗

<i>Clostridium difficile</i>Isolates Resistant to Fluoroquinolones in Italy: Emergence of PCR Ribotype 018Semantic proximity Read ↗

The changes of PCR ribotype and antimicrobial resistance of Clostridium difficile in a tertiary care hospital over 10 years.Semantic proximity Read ↗

Diversity of moxifloxacin resistance during a nosocomial outbreak of a predominantly ribotype ARU 027 Clostridium difficile diarrhea.Semantic proximity Read ↗

PCR ribotype prevalence and molecular basis of macrolide-lincosamide-streptogramin B (MLSB) and fluoroquinolone resistance in Irish clinical Clostridium difficile isolatesSemantic proximity Read ↗

Emergence and Spread of Clostridioides difficile Isolates With Reduced Fidaxomicin Susceptibility in an Acute Care Hospital.Semantic proximity Read ↗

In vitro susceptibility of genotypically distinct and clonal Clostridium difficile strains to oritavancin.Semantic proximity Read ↗

Clinical characteristics of relapses and re-infections in Clostridium difficile infection.Semantic proximity Read ↗

A prospective study of risk factors and historical trends in metronidazole failure for Clostridium difficile infection.Semantic proximity Read ↗

Susceptibility of Clostridium difficile Isolates of Varying Antimicrobial Resistance Phenotypes to SMT19969 and 11 Comparators.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.