Article
Dynamic variation in allele-specific gene expression of Paraoxonase-1 in murine and human tissues.
Human molecular genetics - 1 Nov 2008
Parker-Katiraee Layla, Bousiaki Eleni, Monk David, Moore Gudrun E, Nakabayashi Kazuhiko, Scherer Stephen W
Abstract excerpt
Differential allelic expression has been shown to be common in mice, humans and maize, and variability in the expression of polymorphic alleles has been associated with human disease. Here, we describe the differential expression pattern of Paraoxonase-1, a gene involved in lipid metabolism and implicated in the formation of atherosclerotic lesions. We measured the expression of the murine Paraoxonase-1 gene...
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