Article
[Obtaining of the mutant Yarrowia lipolytica strains producing citric acid from glucose].
Prikladnaia biokhimiia i mikrobiologiia - 1 Jan 2000
Finogenova T V, Puntus I F, Kamzolova S V, Lunina Iu N, Monastyrskaia S E, Morgunov I G, Boronin A M
Abstract excerpt
The possibility of obtaining mutant yeasts Yarrowia lipolytica VKM Y-2373 with increased ability to synthesize citric acid from glucose by using UV irradiation and N-methyl-NT-nitro-N-nitrosoguanidine was studied. Of 1500 colonies of the Y. lipolytica treated with either UV or N-methyl-NT-nitro-N-nitrosoguanidine, three mutants were selected that displayed higher (by 23%) biosynthetic ability as compared with the...
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