A theoretical approach to the large-scale evolution of multicellularity and cell differentiation.

doi:10.1016/j.jtbi.2008.07.006

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

A theoretical approach to the large-scale evolution of multicellularity and cell differentiation.

Journal of theoretical biology - 7 Nov 2008

Otsuka Jinya

Abstract excerpt

In contrast to Darwinian evolution in which organisms have been selected by the instantaneous judgment of advantage or disadvantage for a mutated gene, the large-scale evolution of multicellular organisms by drastic changes in their genomes to produce new genes is theoretically formulated on the basis of the new concept of 'biological activity'. The 'biological activity' of an organism is a macroscopic quantity...

Topics

Animals
Cell Communication
Cell Differentiation
Energy Metabolism
Environment
Evolution, Molecular
Genome
Models, Biological
Mutation
Origin of Life
Thermodynamics

Source

Open in PubMed

Identifiers

PMID: 18662703
DOI: 10.1016/j.jtbi.2008.07.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics