Article
The cell as the mechanistic basis for evolution.
Wiley interdisciplinary reviews. Systems biology and medicine - 1 Jan 2000
Torday J S
Abstract excerpt
The First Principles for Physiology originated in and emanate from the unicellular state of life. Viewing physiology as a continuum from unicellular to multicellular organisms provides fundamental insight to ontogeny and phylogeny as a functionally integral whole. Such mechanisms are most evident under conditions of physiologic stress; all of the molecular pathways that evolved in service to the vertebrate...
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