Article
Mapping the progression of progranulin-associated frontotemporal lobar degeneration.
Nature clinical practice. Neurology - 1 Aug 2008
Rohrer Jonathan D, Warren Jason D, Barnes Josephine, Mead Simon, Beck Jonathan, Pepple Tracey, Boyes Richard, Omar Rohani, Collinge John, Stevens John M, Warrington Elizabeth K, Rossor Martin N, Fox Nick C
Abstract excerpt
BACKGROUND: A 55-year-old woman was followed over a 13-year period as part of a longitudinal study of people at risk for familial dementia. She was a member of a family with an autosomal dominant familial dementia that fulfilled consensus criteria for frontotemporal lobar degeneration. The patient was initially asymptomatic but developed progressive behavioral and cognitive decline characterized by apathy,...
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