Article
[A five-year analysis of HBV mutations in a multidrug-resistant patient with chronic hepatitis B].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Jul 2008
Li Xiao-dong, Wang Lin, Li Fan, Mao Pan-yong, Wang Hui-fen, Xu Dong-ping
Abstract excerpt
OBJECTIVE: To investigate HBV mutations in reverse transcriptase (RT) gene and precore/basal core promoter (PC/BCP) regions in a chronic hepatitis B patient and to analyze the link between the mutations and drug resistance or HBeAg sero-conversion. METHODS: Eighteen serum samples were collected from a chronic hepatitis B patient during his 14 hospitalizations from June 2002 to September 2007. HBV DNA was...
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