Article
Effects of the disruption of the HSP70-II gene on the growth, morphology, and virulence of Leishmania infantum promastigotes.
International microbiology : the official journal of the Spanish Society for Microbiology - 1 Jun 2008
Folgueira Cristina, Carrión Javier, Moreno Javier, Saugar Jose M, Cañavate Carmen, Requena Jose M
Abstract excerpt
The 70-kDa heat shock protein (HSP70) is highly conserved among both prokaryotes and eukaryotes and plays essential roles in diverse cellular functions not only under stress but also under normal conditions. In the protozoan Leishmania infantum, the causative agent of visceral leishmaniasis, HSP7...
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