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Article

Tumour glycolysis: the many faces of HIF.

Journal of theoretical biology - 21 Sept 2008

Kelly Catherine, Smallbone Kieran, Brady Michael

Abstract excerpt

We present a model for tumour metabolism that incorporates both microenvironmental (extracellular) and oncogenic (intracellular) influences. We explore the effects of the interaction between the hypoxic microenvironment and intracellular signalling on the glycolytic response of tumour tissue, finding that the glycolytic state is dependent on a delicately balanced interplay between the cellular hypoxic response,...

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Share to Cell Hypoxia
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Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose

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Share to Hypoxia-Inducible Factor 1, alpha Subunit

Share to Intercellular Signaling Peptides and Proteins

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Source

Identifiers

PMID: 18639251
DOI: 10.1016/j.jtbi.2008.05.025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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