Article
Plant immunity requires conformational changes [corrected] of NPR1 via S-nitrosylation and thioredoxins.
Science (New York, N.Y.) - 15 Aug 2008
Tada Yasuomi, Spoel Steven H, Pajerowska-Mukhtar Karolina, Mou Zhonglin, Song Junqi, Wang Chun, Zuo Jianru, Dong Xinnian
Abstract excerpt
Changes in redox status have been observed during immune responses in different organisms, but the associated signaling mechanisms are poorly understood. In plants, these redox changes regulate the conformation of NPR1, a master regulator of salicylic acid (SA)-mediated defense genes. NPR1 is sequestered in the cytoplasm as an oligomer through intermolecular disulfide bonds. We report that S-nitrosylation of NPR1...
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