Retroviruses and primate evolution.

doi:10.1002/(SICI)1521-1878(200002)22:2<161::AID-BIES7>3.0.CO;2-X

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Article

Retroviruses and primate evolution.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 2000

Sverdlov E D

Abstract excerpt

Human endogenous retroviruses (HERVs), probably representing footprints of ancient germ-cell retroviral infections, occupy about 1% of the human genome. HERVs can influence genome regulation through expression of retroviral genes, either via genomic rearrangements following HERV integrations or through the involvement of HERV LTRs in the regulation of gene expression. Some HERVs emerged in the genome over 30 MYr...

Topics

Animals
Biological Evolution
Endogenous Retroviruses
Gene Expression Regulation
Genome, Human
HIV
Humans
Mutation
Primates
Retroelements
Terminal Repeat Sequences
Time Factors

Source

Open in PubMed

Identifiers

PMID: 10655035
DOI: 10.1002/(SICI)1521-1878(200002)22:2<161::AID-BIES7>3.0.CO;2-X

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