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Article

Different outcome of six homozygotes for prothrombin A20210A gene variant.

Journal of translational medicine - 15 Jul 2008

Di Micco Pierpaolo, Di Fiore Rosanna, Niglio Alferio, Quaranta Sandro, Angiolillo Antonella, Cardillo Giuseppe, Castaldo Giuseppe

Abstract excerpt

Prothrombin G20210A gene variant (FII G20210A) is a risk factor for venous thrombotic disease while conflicting results have been reported for the risk of arterial thrombotic events. However, vascular episodes were absent in up to 40% of the 67 homozygotes for the G20210A described so far, which indicates that the clinical expression depends on additional risk/trigger factors. We describe six homozygotes for the...

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Identifiers

PMID: 18627609
DOI: 10.1186/1479-5876-6-36
PMCID: PMC2483266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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