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Article

The pharmacogenomics of epilepsy

27 Aug 2015

Abstract excerpt

Genetic factors contribute to the high interindividual variability in response to antiepileptic drugs. However, most genetic markers identified to date have limited sensitivity and specificity, and the value of genetic testing in guiding antiepileptic drug (AED) therapy is limited. The best defined indication for testing relates to HLA-B*15:02 genotyping to identify those individuals of South Asian ethnicity who...

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PMID: 26327193
DOI: 10.1586/14737175.2015.1083424

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