Article
Expression of HLA-DQ antigens in the small-intestinal mucosa of patients with coeliac disease.
Scandinavian journal of gastroenterology - 1 Jun 1991
Schweizer J J, Mearin M L, Peña A S, Offerhaus G J, Dreef E J, Roep B O, Bontrop R E, Dooren L J, Lamers C B, Hoedemaeker P J
Abstract excerpt
Studies at the DNA and product level of B-cell lines of coeliac patients have shown a strong association between coeliac disease and the HLA-DQ alpha 2.3 and HLA-DQ beta 2.7 alleles. The monoclonal antisera SFR20-DQ alpha 5 and XIII-358.4, which specifically react with HLA-DQ alpha 2.3 and with HLA-DQ beta 2.3 and -DQ beta 2.7, respectively, have been used to detect the expression of these specificities in the...
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