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Article

A key transcription cofactor on the nascent sex chromosomes of European tree frogs (Hyla arborea).

Genetics - 1 Jul 2008

Niculita-Hirzel H, Stöck M, Perrin N

Abstract excerpt

We show that MED15, a key component of the transcription complex Mediator, lies within the nonrecombining segment of nascent sex chromosomes in the male-heterogametic Hyla arborea. Both X and Y alleles are expressed during embryonic development and differ by three frame-preserving indels (eight amino acids in total) within their glutamine-rich central part. These changes have the potential to affect the...

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Identifiers

PMID: 18622030
DOI: 10.1534/genetics.108.090746
PMCID: PMC2475764

Genes

MED15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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