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Article

Anomalous dopamine release associated with a human dopamine transporter coding variant.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 9 Jul 2008

Mazei-Robison Michelle S, Bowton Erica, Holy Marion, Schmudermaier Martin, Freissmuth Michael, Sitte Harald H, Galli Aurelio, Blakely Randy D

Abstract excerpt

Dopamine (DA) signaling at synapses is tightly coordinated through opposing mechanisms of vesicular fusion-mediated DA release and transporter-mediated DA clearance. Altered brain DA signaling is suspected to underlie multiple brain disorders, including schizophrenia, Parkinson's disease, bipolar disorder, and attention-deficit hyperactivity disorder (ADHD). We identified a pedigree containing two male children...

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Source

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Identifiers

PMID: 18614672
DOI: 10.1523/JNEUROSCI.0473-08.2008
PMCID: PMC2573963

Genes

SLC6A3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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