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Article

Identification of a tumor‐initiating stem cell population in human renal carcinomas

9 Jul 2008

Abstract excerpt

The purpose of the present study was to search for the presence of a tumor-initiating stem cell population in renal carcinomas. Based on the recent identification of mesenchymal stem cells in normal kidneys, we sorted cells expressing the mesenchymal stem cell marker CD105 from 5 human renal carcinomas. Because the CD105(+) but not the CD105(-) population showed enhanced tumorigenicity when injected in severely...

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PMID: 18614581
DOI: 10.1096/fj.08-102590

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