Article
Insight into microevolution of Yersinia pestis by clustered regularly interspaced short palindromic repeats.
PloS one - 9 Jul 2008
Cui Yujun, Li Yanjun, Gorgé Olivier, Platonov Mikhail E, Yan Yanfeng, Guo Zhaobiao, Pourcel Christine, Dentovskaya Svetlana V, Balakhonov Sergey V, Wang Xiaoyi, Song Yajun, Anisimov Andrey P, Vergnaud Gilles, Yang Ruifu
Abstract excerpt
BACKGROUND: Yersinia pestis, the pathogen of plague, has greatly influenced human history on a global scale. Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR), an element participating in immunity against phages' invasion, is composed of short repeated sequences separated by unique spacers and provides the basis of the spoligotyping technology. In the present research, three CRISPR loci were...
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