Article
[Genotyping by CRISPR and regional distribution of Yersinia pestis in Qinghai-plateau from 1954 to 2011].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 6 Mar 2017
Xu X Q, Xin Y Q, Li X, Zhang Q W, Yang X Y, Jin Y, Zhao H H, Jin X, Qi Z Z
Abstract excerpt
Objective: To investigate the CRISPR genotypes (clusters) and regional distribution of Yersinia pestis in Qinghai-plateau. Methods: One hundred and two isolates of Y. pestis isolated from human plague patients, host animal and insect vectors from Qinghai-plateau were selected. The DNAs were extracted using the traditional sodium dodecyl sulfate decomposition and phenol-chloroform method. Three CRISPR loci YPa,...
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