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Article

The combined effects of the 5- HTTLPR and HTR1A rs6295 polymorphisms modulate decision making in schizophrenia patients.

Genes, brain, and behavior - 1 Feb 2013

Gu H, Liu C, Liu C, Chen M, Zhang Q, Zhai J, Wang K, Ji F, Xu Z, Shen Q, Bao X, Chen X, Li J, Dong Q, Chen C

Abstract excerpt

Decision making ability has been reported to be impaired in schizophrenia patients, but no research has examined the genetic bases of this impairment. This study investigated how decision making was affected by the genetic variants in the serotonin transporter gene (triallelic 5- HTTLPR) and serotonin receptor 1A gene (rs6295) and their interaction in 465 schizophrenia patients and 448 healthy controls. The Iowa...

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Source

Identifiers

PMID: 23036158
DOI: 10.1111/j.1601-183X.2012.00866.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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