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Article

Inflaming gastrointestinal oncogenic programming.

Cancer cell - 8 Jul 2008

DeNardo David G, Johansson Magnus, Coussens Lisa M

Abstract excerpt

The etiology of gastrointestinal tumors implicates a role for chronic inflammation in response to pathogenic microflora as a promoting force for full neoplastic progression. Recently, Oguma and coworkers (2008) demonstrated that TNFalpha, derived from recruited macrophages, potentiates Wnt/beta-catenin signaling and gastric carcinogenesis by activating Akt signaling and GSK3beta phosphorylation independent of the...

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Identifiers

PMID: 18598939
DOI: 10.1016/j.ccr.2008.06.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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