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Article

New insights into multiple coagulation factor deficiency from the solution structure of human MCFD2.

Journal of molecular biology - 12 Sept 2008

Guy Jodie E, Wigren Edvard, Svärd Maria, Härd Torleif, Lindqvist Ylva

Abstract excerpt

Human MCFD2 (multiple coagulation factor deficiency 2) is a 16-kDa protein known to participate in transport of the glycosylated human coagulation factors V and VIII along the secretory pathway. Mutations in MCFD2 or in its binding partner, the membrane-bound transporter ERGIC (endoplasmic reticu...

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Source

Identifiers

PMID: 18590741
DOI: 10.1016/j.jmb.2008.06.042

Genes

MCFD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18590741-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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New insights into multiple coagulation factor deficiency from the solution structure of human MCFD2.PMID 18590741Read ↗

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