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Article

The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2008

Nechama Morris, Ben-Dov Iddo Z, Briata Paola, Gherzi Roberto, Naveh-Many Tally

Abstract excerpt

Serum calcium and phosphate concentrations and experimental chronic kidney failure control parathyroid hormone (PTH) gene expression post-transcriptionally through regulated binding of the trans-acting proteins AUF1 and upstream of N-ras (Unr) to an AU-rich element (ARE) in PTH mRNA 3'-untranslated region (3'UTR). We show that the mRNA decay promoting K-homology splicing regulator protein (KSRP) binds to PTH mRNA...

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Source

Identifiers

PMID: 18583400
DOI: 10.1096/fj.08-107250

Genes

PTH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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