Association between PTGS2 polymorphism and autism spectrum disorders in Korean trios.

doi:10.1016/j.neures.2008.05.008

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Article

Association between PTGS2 polymorphism and autism spectrum disorders in Korean trios.

Neuroscience research - 1 Sept 2008

Yoo Hee Jeong, Cho In Hee, Park Mira, Cho Eunchung, Cho Soo Churl, Kim Bung Nyun, Kim Jae Won, Kim Soon Ae

Abstract excerpt

Cyclooxygenase-2 (Cox-2) is an inducible enzyme involved in neuroplasticity and the neuropathology of the central nervous system. This study evaluated the relationship between autism spectrum disorders (ASDs) and polymorphisms of PTGS2 (the gene encoding Cox-2) with 151 Korean family trios including children with ASDs. We found that the A allele of rs2745557 was preferentially transmitted in ASDs (p < 0.01) and...

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Identifiers

PMID: 18579107
DOI: 10.1016/j.neures.2008.05.008

Genes

PTGS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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