Article
Family-based association study between NOS-I and -IIA polymorphisms and autism spectrum disorders in Korean trios.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2009
Kim Hyo-Won, Cho Soo-Churl, Kim Jae-Won, Cho In Hee, Kim Soon Ae, Park Mira, Cho Eun Jeong, Yoo Hee-Jeong
Abstract excerpt
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with a strong genetic component and environmental risk factors. Nitric oxide (NO), which is produced by nitric oxide synthase (NOS), may play a role in the development of ASD. We genotyped nine single nucleotide polymorphisms (SNPs) in the NOS-I gene and nine SNPs in the NOS-IIA gene and carried out the transmission disequilibrium test (TDT)...
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