Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Premature aging of the immune system in children with juvenile idiopathic arthritis

24 Jun 2008

Abstract excerpt

OBJECTIVE: Juvenile idiopathic arthritis (JIA) is an autoimmune disease of the young. The pathogenesis is not completely understood. Premature aging, associated thymic involution, and compensatory autoproliferation could play important roles in the pathogenesis of autoimmunity. We undertook this study to determine whether patients with JIA demonstrate premature immunosenescence. METHODS: To test this hypothesis,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune and Inflammatory Disorders Research
Share to Systemic Lupus Erythematosus Research
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18576332
DOI: 10.1002/art.23599

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Premature aging of the immune system in children with juvenile idiopathic arthritisPMID 18576332Read ↗

Premature Immunosenescence in Rheumatoid Arthritis and Multiple Sclerosis PatientsSemantic proximity Read ↗

Rheumatoid Arthritis, Immunosenescence and the Hallmarks of Aging.Semantic proximity Read ↗

Dysregulated lymphocyte proliferation and differentiation in patients with rheumatoid arthritisSemantic proximity Read ↗

Immune Aging in Rheumatoid ArthritisSemantic proximity Read ↗

Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages.Semantic proximity Read ↗

T cell homeostasis in patients with rheumatoid arthritisSemantic proximity Read ↗

Immunosenescence and rheumatoid arthritis: Does telomere shortening predict impending disease?Semantic proximity Read ↗

The effect of age on the phenotype and function of developing thymocytes.Semantic proximity Read ↗

Frequency and phenotypic analysis of CD4+CD25+ regulatory T cells in children with juvenile idiopathic arthritis.Semantic proximity Read ↗

Immunosenescence is associated with altered gene expression and epigenetic regulation in primary and secondary immune organsSemantic proximity Read ↗

Naïve T Cells in the ElderlySemantic proximity Read ↗

How does age determine the development of human immune-mediated arthritis?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.