Article
Function and transcriptional regulation of the isocitrate lyase in Pseudomonas aeruginosa.
Archives of microbiology - 1 Aug 2008
Kretzschmar Utta, Khodaverdi Viola, Jeoung Jae-Hun, Görisch Helmut
Abstract excerpt
Pseudomonas aeruginosa ATCC 17933 is capable of growing aerobically on ethanol as sole source of carbon and energy. This requires the glyoxylate cycle for replenishing C4-compounds to the TCA cycle. The enzyme isocitrate lyase (ICL) catalyzes the first step of this glyoxylate shunt. Its activity was induced more than 10-fold in response to the carbon sources ethanol or acetate instead of glucose or succinate. We...
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