Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenotype, phenotype, and tumors in patients with isolated hemihyperplasia.

The Journal of pediatrics - 1 Jul 2008

Bliek Jet, Maas Saskia, Alders Mariel, Merks Johannes H M, Mannens Marcel

Abstract excerpt

OBJECTIVE: To investigate whether epigenotyping of patients with isolated hemihyperplasia (IH) can, analogous to genetic screening of patients with Beckwith-Wiedemann syndrome, be used for the prediction of tumor risk and tumor type of individual patients. STUDY DESIGN: Methylation analysis of H19 and KCNQ1OT1 of 73 patients. Questionnaires were sent to referring clinicians. RESULTS: In 75% of the clinically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child, Preschool
Share to Beckwith-Wiedemann Syndrome
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Infant

Share to Models, Genetic

Share to Neoplasms

Share to Uniparental Disomy

Source

Identifiers

PMID: 18571544
DOI: 10.1016/j.jpeds.2007.12.022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Epigenotype, phenotype, and tumors in patients with isolated hemihyperplasia.PMID 18571544Read ↗

Constitutional UPD for chromosome 11p15 in individuals with isolated hemihyperplasia is associated with high tumor risk and occurs following assisted reproductive technologiesSemantic proximity Read ↗

Children with idiopathic hemihypertrophy and beckwith-wiedemann syndrome have different constitutional epigenotypes associated with wilms tumor.Semantic proximity Read ↗

Epigenotyping as a tool for the prediction of tumor risk and tumor type in patients with Beckwith-Wiedemann syndrome (BWS).Semantic proximity Read ↗

Increased tumour risk for BWS patients correlates with aberrant H19 and not KCNQ1OT1 methylation: occurrence of KCNQ1OT1 hypomethylation in familial cases of BWS.Semantic proximity Read ↗

Bilateral pheochromocytomas, hemihyperplasia, and subtle somatic mosaicism: the importance of detecting low-level uniparental disomy.Semantic proximity Read ↗

Constitutional H19 hypermethylation in a patient with isolated cardiac tumor.Semantic proximity Read ↗

Inherited and Sporadic Epimutations at the IGF2-H19 locus in Beckwith-Wiedemann syndrome and Wilms' tumor.Semantic proximity Read ↗

Analysis of paediatric tumour types associated with hemihyperplasia in childhood.Semantic proximity Read ↗

Paternal uniparental disomy in monozygotic twins discordant for hemihypertrophy.Semantic proximity Read ↗

Screening for wilms' tumour in patients with aniridia, Beckwith syndrome, or hemihypertrophySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.