Article
Children with idiopathic hemihypertrophy and beckwith-wiedemann syndrome have different constitutional epigenotypes associated with wilms tumor.
American journal of human genetics - 1 Nov 2005
Niemitz Emily L, Feinberg Andrew P, Brandenburg Sheri A, Grundy Paul E, DeBaun Michael R
Abstract excerpt
Idiopathic hemihypertrophy (IH) is a congenital overgrowth syndrome associated with an increased risk of embryonal cancers in childhood. A related developmental disorder is Beckwith-Wiedemann syndrome (BWS), which increases risk for embryonal cancers, including Wilms tumor. Constitutional epigenetic alterations associated with BWS have been well characterized and include epigenetic alterations of imprinted genes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
