Article
A polymer-based DNA biochip platform for human papilloma virus genotyping.
Journal of virological methods - 1 Jan 2010
Brandstetter Thomas, Böhmer Sebastian, Prucker Oswald, Bissé Emmanuel, zur Hausen Axel, Alt-Mörbe Juliane, Rühe Jürgen
Abstract excerpt
Genotyping of the human papilloma virus (HPV) is from a clinical point of view an important diagnostic task as some genotypes play a major role in the development of cervical carcinoma. So far PCR combined with blotting or in situ labelling is known to be the most accurate and sensitive method for detection and genotyping of HPV infection in clinical samples. However, specificity, cost-efficiency and sensitivity...
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