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Article

Genotype-adjusted familial correlation analysis using three generalized estimating equations.

Statistics in medicine - 20 Nov 2008

Lee Hye-Seung, Paik Myunghee Cho, Lee Joseph H

Abstract excerpt

We analyze familial correlation of a memory score from Caribbean Hispanic families that have multiple family members affected with Alzheimer's disease, adjusting for having at least one APOE-epsilon4 allele, as well as other confounders. To enhance the efficiency of correlation model, this paper proposes an alternative approach for three generalized estimating equations proposed by Yan and Fine (Statist. Med....

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Identifiers

PMID: 18570263
DOI: 10.1002/sim.3344
PMCID: PMC2736642

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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