Article
Published genetic variants in retinopathy of prematurity: random forest analysis suggests a negligible contribution to risk and severity.
Current eye research - 1 May 2008
Dunai György, Vásárhelyi Barna, Szabó Miklós, Hajdú Júlia, Mészáros Gergõ, Tulassay Tivadar, Treszl András
Abstract excerpt
PURPOSE: Our recent investigations suggested association between severe retinopathy of prematurity (ROP) and some genetic polymorphisms contributing to angiogenesis. While these findings may help to identify specific elements in ROP pathogenesis, the predictive value of these genetic variants at birth is unknown. We applied a high-dimensional nonparametric method called random forest technique (RFT) to evaluate...
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