Paternal origin of the chromosomal deletion resulting in Wolf-Hirschhorn syndrome.

doi:10.1136/jmg.28.4.256

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Article

Paternal origin of the chromosomal deletion resulting in Wolf-Hirschhorn syndrome.

Journal of medical genetics - 1 Apr 1991

Quarrell O W, Snell R G, Curtis M A, Roberts S H, Harper P S, Shaw D J

Abstract excerpt

DNA samples were obtained from children with Wolf-Hirschhorn syndrome and their parents to assist with gene mapping studies of 4p16.3 (the region known to contain the Huntington's disease gene). A panel of seven families was studied, using polymorphic DNA markers, to determine the parental origin...

Topics

Adult
Alleles
Chromosome Aberrations
Chromosome Deletion
Chromosome Disorders
Chromosomes, Human, Pair 4
DNA
DNA Probes
Genetic Markers
Humans
Infant
Syndrome

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