Article
Plasminogen alleles influence susceptibility to invasive aspergillosis.
PLoS genetics - 20 Jun 2008
Zaas Aimee K, Liao Guochun, Chien Jason W, Weinberg Clarice, Shore David, Giles Steven S, Marr Kieren A, Usuka Jonathan, Burch Lauranell H, Perera Lalith, Perfect John R, Peltz Gary, Schwartz David A
Abstract excerpt
Invasive aspergillosis (IA) is a common and life-threatening infection in immunocompromised individuals. A number of environmental and epidemiologic risk factors for developing IA have been identified. However, genetic factors that affect risk for developing IA have not been clearly identified. We report that host genetic differences influence outcome following establishment of pulmonary aspergillosis in an...
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