Article
Anti-cyclic citrullinated peptide antibody isotypes in rheumatoid arthritis: association with disease duration, rheumatoid factor production and the presence of shared epitope.
Clinical and experimental rheumatology - 1 Jan 2000
Lakos G, Soós L, Fekete A, Szabó Z, Zeher M, Horváth I F, Dankó K, Kapitány A, Gyetvai A, Szegedi G, Szekanecz Z
Abstract excerpt
OBJECTIVE: Anti-cyclic citrullinated peptide (anti-CCP) antibodies of IgG isotype are specific diagnostic markers of rheumatoid arthritis (RA). Recent evidence also points to their direct involvement in the pathophysiology. Little information is available, however, regarding the isotype distribut...
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