Article
Application of hepatitis B virus (HBV) DNA sequence polymorphisms to the study of HBV transmission.
The Journal of infectious diseases - 1 Aug 1991
Lin H J, Lai C L, Lauder I J, Wu P C, Lau T K, Fong M W
Abstract excerpt
Short sequences in hypervariable regions of the hepatitis B virus (HBV) genome can be used to identify different strains, providing a novel approach to the study of HBV transmission. The nucleotide sequence in positions 2551-2650 (1:EcoRI site) was determined for serum HBV DNA from 96 Chinese children living in Hong Kong and from 38 of their parents. HBV DNA was extracted and sequenced after amplification with...
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