Article
Expression profiling of PBMC-based diagnostic gene markers isolated from vasculitis patients.
DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Aug 2008
Kobayashi Shigeto, Ito Akihiko, Okuzaki Daisuke, Onda Hiroaki, Yabuta Norikazu, Nagamori Ippei, Suzuki Kazuo, Hashimoto Hiroshi, Nojima Hiroshi
Abstract excerpt
Vasculitis (angiitis) is a systemic autoimmune disease that often causes fatal symptoms. We aimed to isolate cDNA markers that would be useful for diagnosing not only vasculitis but also other autoimmune diseases. For this purpose, we used stepwise subtractive hybridization and cDNA microarray analyses to comprehensively isolate the genes whose expressions are augmented in peripheral blood mononuclear cells...
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